Bioplastics
Bioplastics
Kcnn4 Knockout Induces Salivary Gland Fibrosis, Immune Cell Infiltration, and B‐Cell Dysfunction in Mice
11/10/2026 -
Kcnn4 deficiency leads to a marked enlargement of salivary glands with increased collagen deposition. Increased infiltration of CD4+, CD8+ T cells and CD19+ B cells into the salivary glands of...
A Tightly Interlayer Bonded, Synchronously In Situ Co‐Injectable, Wet‐Adhesive, Hierarchically Biofunctionalized Bilayer Hydrogel for Functional Attachment and Orderly Periodontal Regeneration
22/09/2026 -
An interlayer‐bonded, synchronously in situ co‐injectable, wet‐adhesive, hierarchically biofunctionalized bilayer hydrogel was developed for coordinated regeneration of alveolar bone and...
A Sprayable Multifunctional Film Based on EGFR‐Targeting DNA Nanoactivators for Burn Wound Healing
15/09/2026 -
A sprayable bioactive film (STAR) transforms wound coverage from passive protection into active regeneration by integrating an EGFR‐targeting DNA nanoactivator with a silk fibroin (SF)–tannic...
Enhancing the Scalable Manufacturing of Human Mesenchymal Stromal Cells in Dynamic Culture Using Bioactive Heparin/Collagen Layer‐by‐Layer Coated Microcarriers
16/09/2026 -
Graphical Abstract and Lay SummarySuccessful manufacturing of human mesenchymal stromal cells (hMSCs) for cell therapy applications requires large quantities of potent cells per dose. Expansion of...
A novel approach for monitoring the spatial distribution and quantitative analysis of micronutrients in plant tissues using laser ablation ICP-MS imaging
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Quantitative imaging of plant tissues by laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) is hindered by the lack of matrix-matched calibration standards. Established...
Biogenic Silver Nanoparticles‐Loaded Collagen–L‐Lysine Matrices in Gel and Spray Formulations for Improved Skin Wound Repair
09/09/2026 -
ABSTRACTBiogenic silver nanoparticles (AgNPs) are emerging as valuable candidates in biomedical research, offering advantages such as cost‐effectiveness, eco‐friendly preparation methods, and...
Biopolymer Multilayer Structure as a Barrier System for Packaging Paper
08/09/2026 -
ABSTRACTThe transition to sustainable food packaging has accelerated the development of polyfluoroalkyl substance (PFAS)‐free paper barrier coatings as safer alternatives to fluorinated compounds....
Unraveling the Asymmetric Hydration Dynamics and Water‐Mediated Stabilization in Collagen Heterotrimers
31/08/2026 -
ABSTRACTCollagen's triple helix structure is fundamental to the mechanical integrity of bodily tissues, and its stability is vital for optimal physiological function. While the stabilization...
Bioinspired Hemostatic Dressings for Rapid and Safe Bleeding Control Via Nanofiber Bridging of Kaolin and Cotton
26/08/2026 -
Bioinspired nanofiber‐bridging design concurrently ensures robust immobilization of nanoclay and optimal blood‐contacting efficiency, effectively circumventing the detrimental encapsulation...
ROS‐Scavenging Single‐Component Polymeric Nanocarriers for Precision siRNA Delivery in Pulmonary Fibrosis Therapy
19/08/2026 -
A single‐component lung‐targeted nanosystem (PPN@siIL11) is developed to integrate siRNA delivery and ROS scavenging. It overcomes multi‐component carrier drawbacks and achieves high pulmonary...
Multi‐Omics Integration Identifies PTGS2 as a Candidate Diagnostic Biomarker and Precise Therapeutic Target Related to Schisandra chinensis for Osteoarthritis
17/08/2026 -
This study used multi‐layer methods such as network pharmacology, differential expression analysis, functional enrichment and GSEA, molecular docking, single‐cell transcriptomics and virtual...
Secretion Engineering Enables Production of a Structurally Stable and Long‐Continuous Type III Collagen Fragment in Pichia pastoris
16/08/2026 -
ABSTRACTRecombinant humanized type III collagen has attracted increasing interest for biomedical and tissue engineering applications due to its roles in extracellular matrix remodeling and tissue...
Discrimination of plant-based milk alternatives: a pilot study comparing mid and near-infrared spectroscopy
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Plant-based milk alternatives (PBMAs) are expanding rapidly, motivating the development of fast, minimal-prep analytical tools for their analysis. We collected and analyzed (n = 154)...
Evaluation of Wound Healing in Wistar Rat Model via Curcumin-Functionalized Copper Nanoparticle Ointment
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Wound healing remains a major clinical challenge, often requiring treatments that combine antimicrobial, antioxidant, and anti-inflammatory properties. In the present study, a novel topical...
The effect of fenugreek oral capsule on the sleep quality of primiparous women in the postpartum period: a triple‑blind randomized controlled trial
04/08/2026 -
Mitochondrial dysfunction is a primary pathogenic mechanism underlying dopaminergic neuron loss in the nigrostriatal pathway in Parkinson’s disease (PD). To investigate mitochondrion-targeted...
Peptide-targeted cubosome and hexosome nanoassemblies mitigate mitochondrial dysfunction in a MitoPark model
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AbstractMitochondrial dysfunction is a primary pathogenic mechanism underlying dopaminergic neuron loss in the nigrostriatal pathway in Parkinson’s disease (PD). To investigate...
Pathology‐Responsive Self‐Assembling Hydrogel Enabling Spatiotemporally Controlled Exosome Release and Redox Regulation for Intervertebral Disc Regeneration
25/07/2026 -
Turning a destructive enzymatic signal into a therapeutic trigger, this work presents an MMP‐13‐responsive self‐assembling hydrogel for pathology‐matched exosome delivery. By combining...
Highly Efficient Enzymatic Catalytic Transformation for the Synthesis of Rare Ginsenoside Compound K (CK) and Its Bioactivity Study
21/07/2026 -
ABSTRACTAs a principal metabolite of ginsenosides, compound K (CK) exhibits remarkable antioxidant, anti‐inflammatory, antidiabetic, and anticancer bioactivities. However, CK is naturally scarce in...
