Packaging
Packaging
Nanoarchitectonics of Metal–Organic Framework and Nanocellulose Composites for Multifunctional Environmental Remediation
11/07/2025 -
Nanoscale metal–organic frameworks (MOFs) and nanocellulose composites have significant potential for the multi‐functional remediation of the environment. This review focused on the synthesis...
Engineered Coenzyme A Biosynthesis and Butyrate Transporter Drives High‐Efficient Butyrate Synthesis in Escherichia coli
10/07/2025 -
ABSTRACTButyric acid is a four‐carbon fatty acid with a range of applications in chemical, food and pharmaceutical industries. In this study, a heterologous butyrate biosynthetic pathway was...
Protein pellet sample preparation for the analysis of N-glycans of therapeutic proteins
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Profiling of N-glycans of therapeutic proteins is a critical component in the control of biopharmaceutical products. N-Glycosylation, a common post-translational modification has been shown to...
Lipid Nanocarriers of Naringin Dispersed Gel for Topical Application: Development, In Vitro, Ex Vivo, and In Vivo Kinetics Evaluations
08/07/2025 -
Preration and evaluation of Naringin‐nanosructured lipid carrier.ABSTRACTNanostructured lipid carriers (NLCs) have emerged as promising systems for topical drug delivery due to their enhanced...
The Combination of UPLC MS and Derivatization Method for Analysis of Purslane for Ulcerative Colitis In Vivo
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Portulaca oleracea L. (PL) has significant clinical efficacy in treating ulcerative colitis (UC), which significantly affects patientsâ daily life. However, the absorption and...
Assessing food by-products macrocomposition by FTIR microspectroscopy
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Food by-products offer a promising opportunity for extracting valuable compounds that can be used in the food, pharmaceutical, and polymer industries. However, unpredictable variations in the...
Becoming fully circular facilitated by PAT
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Process analytical technologies (PAT) have contributed to helping industrial processes become more efficient, more sustainable, safer, and more reliable for more than two decades. Real-time...
Genetically Engineered Yeast for Enhanced Biodegradation of Î-lactam Antibiotics
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High environmental concentrations of pharmaceuticals, particularly antibiotics, have been observed worldwide, while antibiotic concentrations in the ng/L to µg/L range may adversely affect...
Exploring the Potential Mechanism of Action of Ursolic Acid for Parkinson’s Disease: An Integrative Network Pharmacology, Docking and Molecular Dynamics Study
24/06/2025 -
Airborne laser scanning technology is widely used in photogrammetry and remote sensing, enabling three-dimensional information about objects located on the Earth’s surface to be obtained. In...
Thienopyrimidine: Unveiling the Versatile Potential of a Promising Heterocyclic Scaffold in Drug Discovery
19/06/2025 -
ABSTRACTFused pyrimidine scaffolds serve as a flexible and versatile foundational heterocycle in the field of pharmaceutical development. Thienopyrimidines are a diverse family of molecules...
Anti‐Osteoporosis Activity of Lycopene Through ESR1: Network Pharmacology, Molecular Docking, Imaging Technology, and Experimental Validation
12/06/2025 -
Schematic of the mechanism of LYC in treating osteoporosis through the ESR1/PI3K/AKT pathway. LYC upregulates ESR1 expression and thus leads to the activation of the PI3K/AKT pathway, thereby...
Central Composite Design Based Optimization of Carbohydrate Coated Albumin Nanoparticles for HCC: Synthesis, Extensive Characterization and In Vivo Pharmacokinetic Evaluation
29/05/2025 -
ABSTRACTHepatocellular carcinoma (HCC) is one serious cause of cancer‐associated deaths worldwide. Poor bioavailability and non‐specific targeting of drugs is a challenge. Gemcitabine (GEM) is...
Discovery of 1‐(Cyclopropylmethyl)‐2‐(Dibenzo[b,d]Thiophen‐2‐yl)‐1H‐Benzo[d]Imidazole‐5‐Carboxylic Acid as Orally Bioavailable EP4 Receptor Antagonist
31/05/2025 -
Despite significant research in the past decades, no EP4 antagonist has been approved for human use yet. The scaffold‐hopping approach, in combination with docking studies, synthesis, and...
Atomic Scale Engineering of Multivalence‐State Palladium Photocatalyst for Transfer Hydrogenation with Water as a Proton Source
22/05/2025 -
Photocatalytic transfer hydrogenation is achieved over a multivalence‐state palladium photocatalyst, in which protons generated from photocatalytic water splitting are added to unsaturated double...
Optimizing federated learning efficiency: accelerating model averaging with cluster-based approach using class occurrences - fedCCO
22/05/2025 -
Overweight and obesity are major risk factors for heart failure (HF), contributing to its development through metabolic, neurohormonal, haemodynamic, and inflammatory alterations. While...
Sicher durch die Quartalsabrechnung
20/05/2025 -
Simvastatin is one the most commonly used drugs for treatment of hypercholesterolemia but suffers from low bioavailability (about 5%) owing to poor aqueous solubility and extensive first pass...
Zu Gast in der Praxis von ...
20/05/2025 -
Background Thyroid hormones influence the function of essentially every system of the body, including the cardiovascular and metabolic system. Thyroid hormone replacement with...
Expert panel as reference standard procedure in diagnostic accuracy studies: a systematic scoping review and methodological guidance
13/05/2025 -
Background Adverse drug reactions (ADRs) have a significant impact on the healthcare system worldwide. Underreporting of ADRs is identified as a main issue in pharmacovigilance....
A Comprehensive Review on the Advancements of Dual COX‐2/5‐LOX Inhibitors as Anti‐Inflammatory Drugs
10/05/2025 -
This review explores the latest advancements in dual COX‐2/5‐LOX inhibitors, highlighting their potential as effective anti‐inflammatory agents with improved safety profiles compared to...
Synthesis Methods and Therapeutic Journey of Carprofen and Its Derivatives: A Review
10/05/2025 -
Although it is currently only used in veterinary therapy, carprofen proves to be a molecule with a versatile therapeutic potential for human pharmacotherapy. Moreover, the molecule is a target in the...
