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Bromhexine screening using molecularly imprinted polymers for electrochemiluminescence detection and molecular recognition
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Electrochemiluminescence (ECL) is a highly sensitive detection technique; however, its inherently low selectivity is a significant challenge in analytical and sensing applications. In this study,...
Fucoidan: An Update on Function, Role in Human Health and Applications
09/05/2026 -
Fucoidan is a promising bioactive compound with anti‐inflammatory, anticoagulant, anticancer, antioxidant, antiviral, and cardioprotective properties. In addition, thanks to its epigenetic...
Non‐Invasive Brain Targeted Delivery of Cannabidiol for Alleviating Neuroinflammatory Disease
29/04/2026 -
The glucose‐functionalized nanoparticles (GNPs) are developed for the brain‐targeted delivery of cannabidiol (CBD). GNPs bypass the blood‐brain barrier (BBB) via glucose transporter‐1...
Assessing emerging contaminants in Antarctic benthic marine fauna: a dual mass spectrometry investigation combining targeted and suspect screening approaches
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Antarctica hosts a highly endemic and diverse benthic marine fauna. Despite this biodiversity, the Antarctic marine food web remains structurally simple, rendering the ecosystem particularly...
Dispersive micro-solid-phase extraction coupled to UHPLC-Q-TOF-MS and UHPLC-QqQ-MS for suspect and target screening of illicit drugs and pharmaceuticals in wastewater
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The increasing global consumption of pharmaceuticals and illicit drugs, particularly new psychoactive substances, has resulted in their continuous release into aquatic environments, raising...
5-Methyl etodesnitazene human metabolism: LC-ESI±-HRMS/MS analysis (mono- and di-protonation) of human hepatocyte incubations and positive biospecimens
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The rapid emergence of new synthetic opioids (NSOs), especially potent 2-benzylbenzimidazole derivatives known as nitazenes, poses challenges to public health and toxicologists. Among these...
Recent Advances in Laccase‐Based Nanobiocatalysts for Sustainable Bioremediation Applications
29/04/2026 -
Laccases are the most common multicopper oxidase (EC 1.10.3.2); as a result, they have attracted great interest as natural cleaners for environmental bioremediation purposes. However, the fragile...
Raman Spectroscopy–Based Glucose Feed Control Automates Malic Acid Fermentation
29/04/2026 -
Raman spectroscopy enables automated, closed‐loop glucose feeding for malic acid production with Ustilago trichophora. Online PLS regression of glucose and malic acid provides input for PID control...
Liquid-filled stick microextraction with a built-in acidifier enabling pH-adjustment-free analysis of illegal NSAIDs in herbal extracts
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This study presents a liquid-filled stick microextraction method with a built-in acidifier (LFSME-BA) that enables ready-to-use, pH-adjustment-free extraction of non-steroidal anti-inflammatory...
Enhanced Biosynthesis of Phenolics and Antioxidants by Marine Endophyte Penicillium rubens: Optimization and Bioactivity Evaluation
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Marine-derived endophytic fungi have long been recognised as valuable sources of therapeutic metabolites. In the present study, the endophyte Penicillium rubens strain PrubVJ was studied...
Icaritin Inhibits Malignant Progression and Enhances Ferroptosis and Bortezomib Sensitivity by Suppressing HSP90AA1 Expression in Multiple Myeloma
13/04/2026 -
Icaritin inhibits malignant biological behavior and facilitates ferroptosis and BTZ sensitivity in MM by suppressing HSP90AA1.ABSTRACTMultiple myeloma (MM) is a hematologic malignancy commonly...
Interfacial Super‐Assembled Hetero‐Structured Chiral Nanochannels for Enantioseparation Applications
10/04/2026 -
This review summarizes the development of interfacial super‐assembled hetero‐structured chiral nanochannel membranes for enantioseparation. It highlights construction strategies using 0D to 3D...
UCHL3 Promotes Triple-Negative Breast Cancer Metastatic Potential Through Enhancing Cell Migration and Invasion
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Ubiquitin carboxyl-terminal hydrolase L3 (UCHL3), a key deubiquitinating enzyme of the UCH family, has been implicated in DNA repair in breast cancer; however, its role in regulating cell...
Assessing the performance of weak and strong ion exchange solid-phase extraction and data mining tools to identify congeners and transformation products in municipal wastewaters by non-targeted analysis
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Identifying contaminants in complex chemical mixtures requires powerful non-targeted analysis methods and tools, especially when it comes to detecting novel transformation products (TPs) and...
Spatial localization and pharmacodynamic assessment of intracrine androgen metabolism in CRPC xenograft tumor tissues upon active vitamin D treatment
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Castrate-resistant prostate cancer (CRPC) progression is driven by intracrine androgen synthesis despite low circulating androgens. This study investigates the effects of active vitamin D...
Development of a metabolomic LC-QTOF method for bioactive compound production control in plant cell cultures
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The search for sustainable and environmentally friendly production processes drives the development of innovative biotechnological solutions, such as the use of plant cell cultures in controlled...
