Materials
Materials
Polyphenol-Rich Mangosteen Pericarp Extract Attenuates Metabolic and Reproductive Dysfunction in High-fat Diet and Streptozotocin-induced Obese-Diabetic Male Rats: A Preliminary Study
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Obesity has emerged as a substantial socioeconomic challenge, imposing considerable burdens on healthcare systems worldwide, thereby necessitating continued efforts to identify effective and...
Poly(Lactic Acid) Nanofiber Membrane Loaded with Tannins from Charred Sanguisorbae Radix with Antioxidant and Antibacterial Activities for Potential Wound Healing Applications
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Charred Sanguisorbae Radix (CSR) is a well-known traditional Chinese medicine clinically used to treat conditions such as burns and bleeding, with tannins being its main active ingredients....
Effects of Ethanolic Lyophilized and Nanoparticle Extracts of Cilo Wormwood (Artemisia haussknechtii Boiss.) Leaves on Histopathological Findings Antioxidant Defence System and Serum Biomarker Constituents in Diabetic Rats
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Molecular and structural abnormalities triggered by oxidative stress are key determinants of diabetes pathophysiology, and research into natural therapeutic agents targeting these mechanisms is...
Antioxidant Fractions From Leptocarpha rivularis Using Sequential Supercritical Extraction
01/06/2026 -
Leptocarpha rivularis is a medicinal plant whose extract has been used in health care, as it contains important bioactive compounds. Sequential supercritical extraction is a method where the solvent...
Punica Granatum Seed Oil Mitigates Aflatoxin B1âinduced Oxidative Stress and Caspase-associated Apoptosis in HepG2 Cells
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Aflatoxin B1 (AFB1)âdriven oxidative stress and apoptosis are central to hepatocellular carcinoma, yet cytoprotective nutraceutical matrices remain underexplored. We evaluated whether...
Selenium Nanoparticles Functionalized with Glycosmis pentaphylla Extract Attenuate Hepatic Fibrosis Through Modulation of Oxidative Stress and Anti-Inflammatory Responses
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Hepatic fibrosis, a progressive scarring of liver tissue triggered by persistent oxidative injury and inflammatory cascades, poses a pressing clinical burden with few effective remedies. This...
Salidroside Attenuates High-Altitude Hypoxic Myocardial Injury Through Modulation of Oxidative Stress and AKT/GSK-3β Signaling Pathways
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Hypoxia-related myocardial injury is characterized by oxidative stress, mitochondrial dysfunction, and apoptosis, ultimately resulting in impaired cardiac structure and function. Salidroside...
Antioxidant Proline Carbon Dot‐Composited Poly(L‐methionine) Hydrogel Restores Mitophagy to Alleviate Cellular Senescence in Intervertebral Disc Degeneration
21/05/2026 -
Antioxidant proline carbon dot‐composited poly(L‐methionine) hydrogel restores impaired mitophagy in senescent nucleus pulposus cells by enhancing Parkin activation, improving mitochondrial...
Niosomal Gallic Acid Attenuates Obesity-related Hepatic Steatosis Through Oxidative and Inflammatory Regulation With Associated Autophagy and Hedgehog Pathway Modulation
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Obesity is an epidemic condition that is linked to several health issues, including metabolic disorders, diabetes mellitus, and cardiovascular disease. The anti-inflammatory and antioxidant...
Phenolic Grafting of Oxidized Cellulose Nanofibers Using Ferulic Acid: Structural and Antioxidant Analysis Toward Bioactive Nanomaterials
20/05/2026 -
Explored routes to obtain radical‐induced cellulose nanofibers grafted with ferulic acid (FA‐grafted CNF: phosphorylated nanofibers (pCNF) and TEMPO‐oxidized nanofibers (oCNF)). The...
A Dual‐Targeting Strategy Against ROS and GSK‐3β With a PEGylated Fullerene/Smart Hydrogel Synergistic System for Diabetic Bone Regeneration
14/05/2026 -
Schematic illustration of using PEGylated Fullerene/Smart Hydrogel for Diabetic Bone Regeneration.ABSTRACTDiabetic bone regeneration remains a significant clinical challenge due to a hostile...
UHPLC/HRMS-Based Metabolomic Profiling, Antioxidant, and Antibacterial Activity of Dendrobium crumenatum from the Different Regions of Indonesian Conservation Areas
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Dendrobium crumenatum grows extensively in Indonesia, with certain specimens preserved in nature conservation areas such as the Bogor Botanical Gardens (BBG) and the Ujung Kulon National...
In Vitro Evaluation of Novel Synthetic BenzimidazoliumâChalcone Hybrids: Antioxidant and Regenerative Effects in Diabetic Wound Healing
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The prevalence of diabetes mellitus (DM) is increasing daily worldwide. DM patients suffer from numerous complications, including the development of chronic wounds that can lead to amputation....
Dietary Chlorogenic Acid and Omega-3 Relieve Methotrexate-Induced Lung Injury Through Modulation of SIRT1/ PGC-1α/ NF-κB Signaling Axis
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Methotrexate (MTX) is a pivotal chemotherapeutic drug which is also used to treat serious chronic inflammatory disorders. However, it causes perilous pulmonary injury. This study aimed to explore...
Hydrochemical characterization and water quality indexing for sustainable agriculture: the case of Kibwe River, Karonga
12/05/2026 -
Soil salinity limits barley productivity, worsened by domestication bottlenecks that reduced stress-adaptive diversity. We employed a multi-origin introgression strategy using 21 wild Hordeum...
High‐Level Production of Ergothioneine in Yarrowia lipolytica via Systematic Metabolic Engineering Strategies
11/05/2026 -
ABSTRACTErgothioneine (ERG), a food‐derived antioxidant and cytoprotectant, has broad application prospects in food, nutraceuticals, cosmetics, and biomedical fields. The growing market demand for...
Unlocking salt tolerance from Fertile Crescent wild barley: evolutionary and physiological mechanisms in introgressed lines
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AbstractSoil salinity limits barley productivity, worsened by domestication bottlenecks that reduced stress-adaptive diversity. We employed a multi-origin introgression strategy using 21 wild...
Fucoidan: An Update on Function, Role in Human Health and Applications
09/05/2026 -
Fucoidan is a promising bioactive compound with anti‐inflammatory, anticoagulant, anticancer, antioxidant, antiviral, and cardioprotective properties. In addition, thanks to its epigenetic...
