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Research on the Particle Breakage Mechanism in High-Speed Shear Wet Granulation
24/03/2023 - During the operation of a high-speed shear wet granulator, the rotation of the granulation components leads to the emergence of the phenomenon of particle breakage, which results in changes in...
Challenges in the Simulation of Drying in Fluid Bed Granulation
13/02/2023 - Fluid bed granulation is faced with a high level of complexity due to the simultaneous occurrence of agglomeration, breakage, and drying. These complexities should be thoroughly investigated through...
Review of CFD-DEM Modeling of Wet Fluidized Bed Granulation and Coating Processes
26/01/2023 - Wet fluidized bed granulation and coating processes have been widely used in the pharmaceutical and food industries. The complex gas–solid flow coupled with heat and mass transfer in...
Study on the physical mechanical properties and freeze-thaw resistance of artificial phase change aggregates
25/04/2022 - Phase change material (PCM) is often mixed into concrete as artificial aggregate. Developing artificial phase change aggregates (APCA) with excellent freeze–thaw resistance is a key for the...
Novel preparation approach with a 2-step process for spherical particles with high drug loading and controlled size distribution using melt granulation: MALCORE®
- A novel approach for preparing drug-containing particles (DCPs) with controlled size distribution and high drug loading was developed using melt granulation. This approach comprises two steps....
CFD-DEM Simulation of a Coating Process in a Fluidized Bed Rotor Granulator
02/09/2020 - Coating of particles is a widely used technique in order to obtain the desired surface modification of the final product, e.g., specific color or taste. Especially in the pharmaceutical industry,...
Effect of Biodegradable Binder Properties and Operating Conditions on Growth of Urea Particles in a Fluidized Bed Granulator
20/07/2019 - Granulation is an important step during the production of urea granules. Most of the commercial binders used for granulation are toxic and non-biodegradable. In this study, a fully biodegradable and...

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